Manager, Supply Chain Shipping and Logistics

Company: Initial Therapeutics, Inc.
Location: San Diego
Posted on: April 2, 2025

Job Description:

Job Title:Manager, Supply Chain Shipping and LogisticsLocation:San Diego, CA / Hybrid / RemotePosition type:FLSA:Full timeExemptDepartment:Finance ID:Technical Development & Operations7625-Q224-32Profoundly Improve People's lives by Revolutionizing the Delivery of RNA TherapeuticsAt Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people's lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients.Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs). Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline, including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline, and people, please visit and engage with us on and .The OpportunityWe are seeking a Manager, Supply Chain Shipping and Logistics who is experienced, highly energetic, and committed to helping develop and execute Avidity's supply strategy across all clinical programs and supporting the commercial strategies. The Manager Logistics is responsible for overseeing critical logistics functions and projects, including Shipping Validation, Compliance, TIB (Temporary Importation under Bond), vendor management, shipping execution, warehouse management, and cross-functional communication across Avidity's network. This role demands a detailed-oriented professional skilled in the logistics projects, cross-functional leadership, and a strong financial acumen. A strong knowledge of cGMP logistics and distribution, experience working with temperature-controlled (cold chain logistics, manufacturing and distribution operations, and knowledge of cGMP and FDA/EMA guidelines is required. This position will work cross-functionally with CMC, legal, finance, regulatory affairs, quality assurance, quality control, and IT.What You Will Contribute

• Shipping Validation
  • Act as the primary Supply Chain Subject Matter Expert (SME) for shipping validation, including shipping qualification and distribution challenge testing (simulated testing)
  • Develop and optimize packaging solutions to enhance product integrity during transit
  • Collect, analyze, and evaluate validation data to ensure accuracy and compliance
  • Conduct detailed reviews and approvals of validation protocols
  • Prioritize validation activities to ensure alignment with business-critical timelines and operational efficiency
  • Develop and manage long-term shipping validation plans
  • Provide strong leadership to cross-functional teams to drive validation processes effectively, ensuring clear communication, accountability, and alignment among team members
  • Ensure cross-functional alignment with QA, Regulatory Affairs, Quality Control (QC), PM, and external partners during validation processes
  • Manage external consultants and vendors supporting shipping validation activities
    • Compliance, Customs, and Government Agency alignment
      • Manage and oversee the completion of TIB closures, ensuring adherence to submission deadlines
      • Collaborate with CMOs, external consultants, customs attorney, and relevant internal teams to ensure accurate TIB documentation of material consumption and timely submission of appropriate documents
      • Work closely with external consultants on the current importation prototype revision
      • Ensure thorough understanding and adherence to VAT and US Customs and tariff requirements
      • Ensure compliance with customs regulations and trade laws
        • Financial Management and alignment
          • Oversee logistics budget development, ensure accurate shipping forecast, and adhere to the insurance requirements
          • Collaborate closely with the finance team to maintain financial alignment
            • Shipping Execution
              • Oversee and execute shipments between CMOs and ensure that the quantity and quality are consistent with the shipment plan
              • Ensure that all the end-to-end transportation (pick-up to delivery) is coordinated, documented, and tracked in accordance with the company's shipping process (SOP)
              • Resolve issues related to shipping, customs clearance, and delivery
              • Provide regular updates to internal stakeholders on the status of shipments and delivery schedules
              • Collaborate with internal teams, including CMC, Supply Chain, and Project Management, to ensure that shipments are aligned with production and inventory schedules
              • Responsible for creating and maintaining all shipping documents and records
                • Storage and Warehouse Management
                  • Create receiving documents for the third-party storage warehouse(s) in a timely manner
                  • Coordinate the receiving and shipping process with third-party storage warehouse(s)
                  • Manage and track monthly inventory and reconcile as necessary
                    • Others
                      • Lead and manage logistics-related projects
                      • Analyze cost data to identify opportunities for cost savings and efficiency improvements
                      • Coordinate communication with vendors and the internal finance team, handle any billing issues and disputes, and maintain good working relationshipsWhat We Seek
                        • Bachelor's degree in supply chain, pharmaceutical sciences, engineering, or related field required; Advanced Degree preferred
                        • 2 - 4 years of industry experience within Logistics in the Pharmaceutical or Biotech industry
                        • Experience in managing shipping validation, including shipping qualification and distribution challenge testing
                        • Familiarity with international VAT, US tariff, VAT regulations impacting logistics operations
                        • Demonstrated experience in managing shipping forecast, budget, and insurance
                        • Strong leadership and interpersonal skills, with proven ability to effectively lead and manage cross-functional teams
                        • Experience in temperature-controlled (cold chain) logistics
                        • Experience working with third-party CMOs manufacturing, storage warehouse, and freight forwarders/customs brokers
                        • Proficient in MS Excel and PowerPoint, at a minimum.
                        • Knowledge of Smartsheet, Microsoft Visio
                        • Experience with ERP systems
                        • Highly proactive and organized with attention to detail
                        • Excellent communication and interpersonal skills and the ability to facilitate constructive and expedient problem-solving.
                        • Demonstrated excellent communication (oral and written), teamwork, organizational, interpersonal, and problem-solving skills
                        • Ability to travel as neededWhat We Will Provide to You:
                          • The base salary range for this role is $128,000 - $142,000. The final compensation will be commensurate with relevant experience, skillset, internal equity, and market factors.
                          • Avidity offers competitive compensation and benefits, including the opportunity for annual and spot bonuses, stock options, RSUs, and a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, and LTD and four weeks of time off.
                          • A commitment to learning and development, which includes a variety of programming internally developed by and for Avidity employees, opportunities for job-specific training offered by industry, and an education reimbursement program.Avidity Biosciences10578 Science Center Dr. Suite 125San Diego, CA92121O: 858-401-7900F: 858-401-7901
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Keywords: Initial Therapeutics, Inc., San Diego , Manager, Supply Chain Shipping and Logistics, Executive , San Diego, California