Senior Scientist

Company: Bristol-Myers Squibb
Location: San Diego
Posted on: April 12, 2025

Job Description:

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more careers.bms.com/working-with-us.Position SummaryWe seek an innovative, self-motivated, exceptional scientist to join our Drug Metabolism and Pharmacokinetic (DMPK) department at our San Diego, CA site. The role works with multiple disciplines in drug discovery to achieve in vivo proof-of-concept for target validation, influence drug designs in lead optimization, and ultimately identify drug candidates for advancement into the clinic. The selected candidate will have opportunities to work on multiple modalities, including small molecules, biologics, and antibody-drug conjugates, and develop deep scientific expertise in drug hunting.Key Responsibilities

• Provide strategic and scientific leadership as a DMPK representative in discovery teams to influence chemical tractability through application of predictive ADME models.
• Independently design and conduct DMPK and pharmacokinetic-pharmacodynamic (PK-PD) studies; interpret and present the data to project teams.
• Proactively address project issues and apply model-based approaches to integrate pharmacology and toxicology data for decision-making.
• Effectively represent DMPK function and articulate DMPK-related issues and resolutions at project review and portfolio governance meetings.
• Actively engage and collaborate with cross-functional colleagues within or outside the project teams.
• Knowledge and some experience with generative models applied to multi-parameter optimization (MPO) of small molecules is desired but not required.Qualifications & Experience
• Ph.D. in pharmacokinetics, drug metabolism, pharmacology, or related discipline with a minimum of 2 years of experience or MS with 5+ years of industrial experience, or BS with 7+ years of industrial experience.
• Broad understanding of ADME and PK/PD principles and experience in supporting drug discovery as a DMPK representative.
• An agile learner with scientific curiosity and strong problem-solving skills.
• Excellent interpersonal, organizational, oral/written communication skills.
• A strong team player with ability to collaborate and build trustworthy relationships with other disciplines for idea generation, issue resolution and program advancement.If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients' lives through science, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role.Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information https://careers.bms.com/california-residents/.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
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Keywords: Bristol-Myers Squibb, San Diego , Senior Scientist, Other , San Diego, California